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A primary limitation on the popular utilization of oral amiodarone prophylaxis, however, may be the necessity of the 7-working day preoperative cure period of time. Irrespective of whether an accelerated loading routine of amiodarone about a duration of a person to 2 times just before surgical treatment could possibly be productive and Secure in avoiding postoperative atrial fibrillation stays to generally be identified.
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A second limitation would be that the administration of atrial fibrillation was directed via the attending cardiac surgeon. It can be done that a uniform protocol of atrial-fibrillation management might have decreased the length of clinic continue to be; on the other hand, because randomization was blinded, it truly is inconceivable that the longer average healthcare facility stay in the placebo group was attributable to a more protracted procedure regimen for atrial fibrillation.
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